℞ Prescription injectable Neurology
VALPO-CS
Sodium Valproate Injection IP
Trusted Solution for Seizure Control in Critical Care
100 mg/ml Injection (Concentrate for Infusion)
- Effective Seizure Control
- Stabilizes Neuronal Activity
- Well Tolerated in Critical Care
Specifications
| Composition | Each ml contains Sodium Valproate IP 100 mg |
|---|---|
| Strength | 100 mg/ml |
| Dosage form | Injection (Concentrate for Infusion) |
| Pack size | 1 Vial (5 ml) |
| Route | For Intravenous Infusion Only |
| Storage | Store below 25°C. Protect from light. Keep out of reach of children. |
Indications
- Treatment of epileptic seizures (generalized, partial and other seizure types)
- Status epilepticus (adjunctive therapy)
- Bipolar disorder (acute maniaunder specialist guidance)
- Seizure prophylaxis in neurosurgical patients
- Useful in critical care settings for seizure control
Mechanism of action
Sodium Valproate increases the level of GABA (Gamma-Aminobutyric Acid) in the brain by inhibiting GABA transaminase and modulating sodium and calcium channels, thereby reducing neuronal excitability and preventing the spread of abnormal electrical activity.
Dosage and administration
- To be administered by slow intravenous infusion diluted in suitable IV fluids as per clinical protocol.
- Dose and duration as directed by the Physician.
- For single use only.
- Use only under medical supervision.
Safety information
- For I.V. use only.
- Use under strict medical supervision.
- Generally well tolerated; adverse effects are rare.
- Use with caution in patients with hepatic impairment.
- Refer to full prescribing information for contraindications, precautions and adverse effects.
For use by registered medical practitioners, hospitals and laboratories only. Refer to the full prescribing information before use.
