℞ Prescription injectable Steroids
Pradnext 500
Methylprednisolone Sodium Succinate for Injection USP
Potent Corticosteroid for Acute Inflammatory Conditions
500 mg/vial Lyophilized powder for injection
- Powerful Anti-inflammatory Action
- Immunosuppressive Effect
- Rapid Symptom Relief
- Suitable for Critical Care Applications
- Trusted Quality for Better Clinical Outcomes
Specifications
| Composition | Each vial contains Methylprednisolone Sodium Succinate USP 500 mg |
|---|---|
| Strength | 500 mg/vial |
| Dosage form | Lyophilized powder for injection |
| Pack size | 500 mg Vial with Sterile Water for Injection (as per pack) |
| Route | Intramuscular (I.M.) / Intravenous (I.V.) use only |
| Storage | Store below 25°C. Protect from light. |
Indications
- Acute exacerbations of bronchial asthma
- Severe allergic reactions and anaphylaxis (adjunct)
- Autoimmune and inflammatory disorders (e.g. rheumatoid arthritis, lupus, vasculitis)
- Neurological conditions (e.g. multiple sclerosis, acute spinal cord injury)
- Hematological disorders (e.g. immune thrombocytopenia)
- Dermatological conditions (e.g. severe dermatitis, pemphigus)
- Adjunct therapy in shock and critical care conditions
- Prevention of transplant rejection (adjunct)
Mechanism of action
Methylprednisolone is a potent corticosteroid that inhibits multiple inflammatory pathways by suppressing the release of pro-inflammatory cytokines, reducing leukocyte migration, and stabilizing lysosomal membranes, thereby providing strong anti-inflammatory and immunosuppressive effects.
Dosage and administration
- Dose and duration as directed by the Physician.
- For Intramuscular or Intravenous use only.
- Reconstitute with sterile water for injection as per protocol.
- Use under strict medical supervision.
Safety information
- For single use only.
- Use under medical supervision.
- Use with caution in patients with infections, diabetes, hypertension and peptic ulcer.
- Refer to full prescribing information.
For use by registered medical practitioners, hospitals and laboratories only. Refer to the full prescribing information before use.
