℞ Prescription injectable Steroids
Pradnext 125
Methylprednisolone Sodium Succinate for Injection USP
Rapid Control of Inflammation for Better Outcomes
125 mg/vial Lyophilized powder for injection
- Powerful Anti-Inflammatory Action
- Rapid Symptom Relief
- Trusted in Critical Care Settings
Specifications
| Composition | Each vial contains Methylprednisolone Sodium Succinate USP 125 mg |
|---|---|
| Strength | 125 mg/vial |
| Dosage form | Lyophilized powder for injection |
| Pack size | 1 Vial (125 mg) with Sterile Water for Injection (as per pack) |
| Route | Intramuscular (I.M.) / Intravenous (I.V.) use only |
| Storage | Store below 25°C. Protect from light. |
Indications
- Acute exacerbations of bronchial asthma & COPD
- Severe allergic reactions and anaphylaxis (adjunct)
- Inflammatory and autoimmune disorders (e.g. rheumatoid arthritis, lupus, vasculitis)
- Neurological conditions (e.g. multiple sclerosis, acute spinal cord injury)
- Dermatological conditions (e.g. severe dermatitis, pemphigus)
- Adjunct therapy in shock and critical care conditions
- Reduction of inflammation, edema and immune responses
- Used in various acute and chronic inflammatory conditions
Mechanism of action
Methylprednisolone is a potent corticosteroid that inhibits multiple inflammatory pathways by decreasing the production of pro-inflammatory cytokines, reducing leukocyte migration and stabilizing lysosomal membranes, thus producing strong anti-inflammatory, immunosuppressive and anti-allergic effects.
Dosage and administration
- Dose and duration as directed by the Physician.
- For intramuscular or intravenous use only.
- Reconstitute with sterile water for injection as per protocol.
- Administer under medical supervision.
- Dose to be individualized based on clinical condition.
Safety information
- For single use only.
- Use under strict medical supervision.
- Use with caution in patients with infections, diabetes, hypertension, peptic ulcer and psychiatric disorders.
- Not recommended in systemic fungal infections.
- Refer to full prescribing information.
For use by registered medical practitioners, hospitals and laboratories only. Refer to the full prescribing information before use.
